Miljöpåverkan
Atropin
Miljörisk:
Risk för miljöpåverkan av atropin kan inte uteslutas då ekotoxikologiska data saknas.
Nedbrytning:
Det kan inte uteslutas att atropin är persistent, då data saknas.
Bioackumulering:
Atropin har låg potential att bioackumuleras.
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Detaljerad miljöinformation
Environmental Risk Classification
Predicted Environmental Concentration (PEC)
PEC is calculated according to the following formula:
PEC (μg/L) = (A*109*(100-R))/(365*P*V*D*100) = 1.37*10-6*A(100-R)
PEC = 0,0001 μg/L
Where:
A = 0.7699 kg (0.7699 kg atropine sulphate (monohydrate))(total amount API in Sweden year 2022, data from IQVIA). (Ref. 1)
R = removal rate = 0% (no data available)
P = number of inhabitants in Sweden = 10*106
V (L/day) = volume of waste water per capita and day = 200 (ECHA default) (Ref. 2)
D = factor for dilution of waste water by surface water flow = 10 (ECHA default) (Ref. 2)
Ecotoxicological studies
No ecotoxicological data available.
Degradation
No degradation data available.
Bioaccumulation
Log D = -0,61 at pH 7.4 which justifies use of the phrase “Atropine has low potential for bioaccumulation”. (Ref. 3)
References:
1. Data from IQVIA (sales data for atropine sulphate (monohydrate) in 2022).
2. ECHA, European Chemicals Agency. Guidance on information requirements and chemical safety assessment. Ver 2.1, 2011.
3. http://www.chemspider.com/Chemical-Structure.10194105.html?rid=cb467ac6-3f71-44f4-bc5e-a5ebf3c38497&page_num=0