Miljöpåverkan (Läs mer om miljöpåverkan)
Mikafungin
Miljörisk:
Risk för miljöpåverkan av micafungin kan inte uteslutas då ekotoxikologiska data saknas.
Nedbrytning:
Det kan inte uteslutas att micafungin är persistent, då data saknas.
Bioackumulering:
Det kan inte uteslutas att micafungin kan bioackumuleras, då data saknas.
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Detaljerad miljöinformation
Environmental Risk Classification
Predicted Environmental Concentration (PEC)
PEC in water is calculated according to the following formula:
PEC [µg/L] = (A*109 *(100-R))/(365*P*V*D*100) = 1,5*10-6*A(100-R)
PEC = 0,00015 µg/L
A: 1,03567 kg (total sold amount API in Sweden year 2016, data from QuintilesIMS Health). Reduction of A may be justified based on metabolism data.
R: 0 % removal rate (due to loss by adsorption to sludge particles, by voloatilization, hydrolysis or biodegradation) = 0 if no data is available.
P: 9*106 (number of inhabitants in Sweden)
V: 200 L/day (volume of wastewater per capita and day) (ECHA default) (Ref I)
D: 10 (factor for dilution of waste water by surface water flow) (ECHA default) (Ref I)
References
I. ECHA, European Chemicals Agency. 2008 Guidance on information requirements and chemical safety assessement.
http://guidance.echa.europa.eu/docs/guidance_document/information_requirements_en.htm