Miljöpåverkan (Läs mer om miljöpåverkan)
Acetylcystein
Miljörisk:
Risk för miljöpåverkan av acetylcystein kan inte uteslutas då ekotoxikologiska data saknas.
Nedbrytning:
Det kan inte uteslutas att acetylcystein är persistent, då data saknas.
Bioackumulering:
Acetylcystein har låg potential att bioackumuleras.
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Detaljerad miljöinformation
Environmental Risk Classification
Predicted Environmental Concentration (PEC)
PEC is calculated according to the following formula:
PEC(μg/L) = (A*109*(100-R))/(365*P*V*D*100) = 1.5*10-6*A(100-R)
PEC = 1,33 μg/L
Where:
A = 8861,02 kg (total amount API of acetylcysteine in Sweden year 2017, data from IQVIA). (Ref. 1)
R = removal rate = 0% (no data available)
P = number of inhabitants in Sweden = 9*106
V (L/day) = volume of waste water per capita and day = 200 (ECHA default) (Ref. 2)
D = factor for dilution of waste water by surface water flow = 10 (ECHA default) (Ref. 2)
Ecotoxicological studies
No ecotoxicological data available.
Degradation
No degradation data available.
Bioaccumulation
An estimated Log P of -0,66 (unknown method) (Ref. 3) indicates that Acetylcysteine has low potential for bioaccumulation.
Log P < 4 which justifies use of the phrase “Acetylcysteine has low potential for bioaccumulation”.
References:
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Data from IQVIA ”Consumption assessment in kg for input to environmental classification - updated 2018 (data 2017)”.
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ECHA, European Chemicals Agency. Guidance on information requirements and chemical safety assessment. Ver 2.1, 2011
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Meylan, WM and Howard, PH (1995), ChemID+, US National Library of Medicin, National Institutes of Health